DGKZ anticorps
Aperçu rapide pour DGKZ anticorps (ABIN7581194)
Antigène
Voir toutes DGKZ AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Rabbit polyclonal antibody against human diacylglycerol kinase zeta (DGKζ)
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Réactivité croisée (Details)
- Shown to recognize a ~117kDa protein in wild-type DGK ζ protein with no cross activity to recombinant DGKα Protein.
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Purification
- Serum
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Immunogène
- peptide = LENRQHYQMIQREDQE
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Isotype
- IgG
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Indications d'application
- WB – 1:1000 Other in vitro and cellular applications are possible using this antibody, but have not been verified.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.01% thiomersal
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4 °C for up to 30 days. Aliquot and store at -20 °C if longer storage is necessary. Antibody is stable for at least 2 years when stored at -20 °C. Avoid repeated freeze/thaw cycles.
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- DGKZ (Diacylglycerol Kinase, zeta (DGKZ))
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Autre désignation
- DGK Zeta
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Sujet
- DGK catalyzes a reaction terminating the protein kinase C (PKC)mediated signaling by converting diacylglycerol (DAG) to phosphatidic acid (PA), a signaling lipid which is involved in DNA synthesis, phospholipid synthesis, and regulation of several enzymes. DAG is an intermediate in phospholipid synthesis which functions as an allosteric activator of PKC. Research shows the zeta isoform of DGK undergoes tissue-specific alternative splicing resulting in an elongated N terminus enzyme predominantly in muscle.
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Pathways
- Myometrial Relaxation and Contraction
Antigène
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